Bone Marrow and Hematopoietic Stem Cell Transplantation

Below you will find a collection of articles from Hematology, the ASH Education Program Book, written by experts in the field about the use of bone marrow and hematopoietic stem cell transplants for the treatment of a number of blood disorders, including leukemias, myelodysplastic and myeloproliferative disorders, lymphomas, multiple myeloma, and amyloidosis. Complications of the procedure, such as chronic graft-versus-host disease and other late effects, are also explored. Additionally, information about donating bone marrow for transplants, as well as links to other organizations that facilitate marrow donations or transplantation research, are available on this Web site.

General Information

• Transplantation in Adult ALL (2009)
• Allotransplantation for Chronic Lymphocytic Leukemia (2009)
• Allogeneic Stem Cell Transplantation in Follicular Lymphoma: Recent Progress and Controversy (2009)
• ASH Evidence-Based Guidelines: Is There a Role for Second Allogeneic Transplant After Relapse? (2009)
• Gene Replacement Therapy for Sickle Cell Disease and Other Blood Disorders (2008)
• Epigenetic Modulation and Other Options to Improve Outcome of Stem Cell Transplanation in MDS (2008)
• Does High-Dose Therapy and Autologous Hematopoietic Stem Cell Transplantation Have a Role in the Primary Treatment of Peripheral T-Cell Lymphomas? (2008)
• Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia When a Matched Related Donor Is Not Available (2008)
• Reduced-Intensity Stem Cell Transplantation: "...whereof a little More than a little is by much too much." King Henry IV, part 1, I, 2 (2007)
• Stem Cell Transplantation in Mutliple Myeloma (2007)
• Umbilical Cord Blood (UCB) Transplantation: An Alternative to the Use of Unrelated Volunteer Donors? (2007)
• GVHD—The Nuts and Bolts (2007)
• Umbilical Cord Blood Transplantation: A New Alternative Option (2005)
• Reduced-Intensity Conditioning Regimens for Hematologic Malignancies: What Have We Learned over the Last 10 Years? (2005)
• Haploidentical Stem Cell Transplantation: The Always Present but Overlooked Donor (2005)
• Evaluation of Hematopoietic Stem Cell Donors (2005)
• Supportive Care (2004)
• New Developments in Allotransplant Immunology (2003)

Leukemias and Myelodysplastic/Myeloproliferative Disorders

• The Changing Classification of Myelodysplastic Syndromes: What’s in a Name? (2009)
• Treatment of MDS: Something Old, Something New, Something Borrowed... (2009)
• Supportive Care and Chelation Therapy in MDS: Are We Saving Lives or Just Lowering Iron? (2009)
• Epigenetic Modulation and Other Options to Improve Outcome of Stem Cell Transplantation in MDS (2008)

Lymphomas

• Allogeneic Stem Cell Transplantation In Follicular Lymphoma: Recent Progress and Controversy (2009)
• Novel Therapies and Role of Transplant in the Treatment of Peripheral T-Cell Lymphomas (2008)
• Management of Hodgkin Lymphoma in Relapse after Autologous Stem Cell Transplant (2008)
• Reduced-Intensity Regimens in Allogeneic Stem-Cell Transplantation for Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia (2006)
• Low-Grade Lymphoma (2004)

Other Disorders

• Reduced-Intensity Regimens in Allogeneic Hematopoietic Stem Cell Transplantation for Hemoglobinopathies (2006)
• Hematopoietic Cell Transplantation for Benign Hematological Disorders and Solid Tumors (2003)
• The Hematologist and Radiation Casualties (2003)

Late Effects

• Late Critical Problems in Transplantation: An Historical Perspective (2008)
• Late Pulmonary, Cardiovascular, and Renal Complications after Hematopoietic Stem Cell Transplantation and Recommended Screening Practices (2008)
• Recognizing and Managing Chronic Graft-Versus-Host Disease (2008)
• Old and New Cancers after Hematopoietic-Cell Transplantation (2008)

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