Myeloproliferative Disorders

Below you will find a collection of articles from Hematology, the ASH Education Program Book, written by experts in the field about current treatments for myeloproliferative disorders (MPD), including essential thrombocythemia, myelofibrosis, and polycythemia. This Web site also provides a link to an organization that informs and supports MPD patients and their families.

Myeloproliferative

• Therapeutic Potential of JAK2 Inhibitors (2009)
• Philadelphia Chromosome-Negative Myeloproliferative Disorders: An Historical Perspective (2008)
• The JAK2V617F Mutation in Polycythemia Vera and Other Myeloproliferative Disorders: One Mutation for Three Diseases? (2008)
• New Advances in the Pathogenesis and Therapy of Essential Thrombocythemia (2008)
• From Palliation to Epigenetic Therapy in Myelofibrosis (2008)

Essential Thrombocytosis/Thrombocythemia (High Platelet Count)

• Pathogenesis and Management of Essential Thrombocythemia (2009)
• Thrombocytosis (2009)
• New Advances in the Pathogenesis and Therapy of Essential Thrombocythemia (2008)
• Thrombocytosis and Thrombosis (2007)
• Management of Polycythemia Vera and Essential Thrombocythemia (2005)

Myelofibrosis

• From Palliation to Epigenetic Therapy in Myelofibrosis (2008)
• Biology and Treatment of Primary Myelofibrosis (2007)

Other

• Myeloproliferative Disease in Pregnancy and Other Management Issues (2006)
• Recent Advances in the Diagnosis and Treatment of Hypereosinophilic Syndromes (2005)
• Platelets and Thrombosis in Myeloproliferative Diseases (2005)

Pathophysiology / Diagnositics

• Navigating the Evolving Paradigms in the Diagnosis and Treatment of Myeloproliferative Disorders (2007)
• The Genetic Basis of Myeloproliferative Disorders (2007)
• Role of JAK-STAT Signaling in the Pathogenesis of Myeloproliferative Disorders (2006)
• On the Molecular Origins of the Chronic Myeloproliferative Disorders: It All Makes Sense (2005)

Polycythemia (High Red Blood Cell Count)

• Idiopathic Erythrocytosis: A Disappearing Entity (2009)
• Management of Polycythemia Vera and Essential Thrombocythemia (2005)

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