Disorders of Iron Metabolism

Below you will find a collection of articles from Hematology, the ASH Education Program Book, written by experts in the field about iron deficiency and overload, hemochromatosis, and porphyrias. A lack of sufficient iron can cause anemia; a number of links to organizations that inform and support anemia patients and their families are available online. In addition, more about how iron deficiency affects pregnant women and older adults is also provided on this Web site.

Iron Overload

• Hereditary Hemochromatosis: Insights From the Hemochromatosis and Iron Overload Screening (HEIRS) Study (2009)
• Molecular Mechanisms of Normal Iron Homeostasis (2009)
• Non-Invasive Assessment of Tissue Iron Overload (2009)
• Supportive Care and Chelation Therapy in MDS: Are We Saving Lives or Just Lowering Iron? (2009)

Iron Deficiency and Hemochromatosis 

• Hereditary Hemochromatosis: Insights From the Hemochromatosis and Iron Overload Screening (HEIRS) Study (2009)
• Iron in Hematology: An Historical Perspective (2008)
• The Regulation of Hepcidin and Its Effects on Systemic and Cellular Iron Metabolism (2008)
• The Anemia of Inflammation: Mechanisms and Management (2008)
• Clinical Relevance of Anemia and Transfusion Iron Overload in Myelodysplastic Syndromes (2008)
• Hepcidin and Its Role in Regulating Systemic Iron Metabolism (2006)
• Current Approaches to the Management of Hemochromatosis (2006)
• New Advances in Iron Chelation Therapy (2006)

Porphyrias

• Neurovisceral Porphyrias: What a Hematologist Needs to Know (2005)