Bleeding and Platelet Disorders

Below you will find a collection of articles from Hematology, the ASH Education Program Book, written by experts in the field about a variety of bleeding disorders, including hemophilia, von Willebrand disease, platelet disorders, thrombocytopenia, and thrombocytosis. General information about bleeding disorders, as well as specific information on hemophilia and von Willebrand disease, can be found on this Web site. A number of links to organizations that inform and support patients with bleeding disorders and their families are also available.

General Information

• Determinants of Platelet Number and Regulation of Thrombopoiesis (2009)
• Drug-Induced Thrombocytopenia: Pathogenesis, Evaluation, and Management (2009)
• Thrombocytosis (2009)
• Factor XI Deficiency - Resolving the Enigma? (2009)
• Does Helicobacter pylori Eradication Therapy Result in a Platelet Count Improvement in Adults with Immune Thrombocytopenic Purpura Regardless of H pylori Infection? (2008)
• What Is the Evidence for the Off-label Use of Recombinant Factor VIIa (rFVIIa) in the Acute Reversal of Warfarin? (2008)
• Thrombocytosis and Thrombosis (2007)
• Novel Thrombopoietic Agents (2007)
• Aspirin and Clopidogrel Resistance (2007)
• Bleeding and Thrombosis Risks in Plasma Cell Dyscrasias (2007)
• Management of Thrombohemorrhagic Syndromes (THS) in Hematologic Malignancies (2007)
• Double Hazard of Thrombophilia and Bleeding in Leukemia (2007)
• Platelets: Testing, Dosing and the Storage Lesion—Recent Advances (2006)
• Perioperative Evaluation of Bleeding Diathesis (2006)
• Challenges in the Therapeutic Use of a “So-Called” Universal Hemostatic Agent: Recombinant Factor VIIa (2006)
• Bleeding Disorders in Premenopausal Women: (Another) Public Health Crisis for Hematology? (2006)
• Diagnosis and Management of Mild Bleeding Disorders (2005)
• Management of Bleeding Disorders in Children (2005)

Hemophilia and von Willebrand Disease

• Low von Willebrand Factor: Sometimes a Risk Factor and Sometimes a Disease (2009)
• Optimizing Treatment of von Willebrand Disease by Using Phenotypic and Molecular Data (2009)
• Update on Progress and Hurdles in Novel Genetic Therapies for Hemophilia (2007)
• Bleeding Disorders in Premenopausal Women: (Another) Public Health Crisis for Hematology? (2006)
• Acquired Factor VIII Inhibitors: Pathophysiology and Treatment (2006)
• Diagnosis and Management of Mild Bleeding Disorders (2005)
• Management of Bleeding Disorders in Children (2005)
• New Perspectives in Hemophilia Treatment (2005)

Platelet Disorders

• Bleeding Disorders in Premenopausal Women: (Another) Public Health Crisis for Hematology? (2006)
• Acquired Disorders of Platelet Function (2005)
• Diagnosis and Management of Mild Bleeding Disorders (2005)
• Management of Bleeding Disorders in Children (2005)

Thrombocytopenia

• Immune Thrombocytopenia (ITP): An Historical Perspective (2008)
• Viral-Associated Immune Thrombocytopenic Purpura (2008)
• Helicobacter pylori and Chronic ITP (2008)
• The Pathophysiology of ITP Revisited: Ineffective Thrombopoiesis and the Emerging Role of Thrombopoietin Receptor Agonists in the Management of Chronic Immune Thrombocytopenic Purpura (2008)
• TTP and ADAMTS13: When Is Testing Appropriate? (2007)
• Immune Thrombocytopenic Purpura of Childhood (2006)
• ITP in the 21st Century (2006)
• Think of HIT (2006)
• Thrombotic Thrombocytopenic Purpura: A Moving Target (2006)
• Inherited Platelet Disorders (2005)
• Congenital and Acquired Thrombocytopenia (2004)

Thrombocytosis

• Thrombocytosis (2009)
• Thrombocytosis and Thrombosis (2007)

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