Acute Leukemias

Below you will find a collection of articles from Hematology, the ASH Education Program Book, written by experts in the field about current treatments for acute leukemia. To learn more about leukemia, please see our general information page about the disease. A number of links to organizations that inform and support patients with leukemia and their families are also available.

General

• Darwin and Evolutionary Tales in Leukemia (2009)
• Management of Thrombohemorrhagic Syndromes (THS) in Hematologic Malignancies (2007)
• Double Hazard of Thrombophilia and Bleeding in Leukemia (2007)

Acute Lymphoblastic (Lymphocytic) Leukemia (ALL)

• The Role of NOTCH1 Signaling in T-ALL (2009)
• Transplantation in Adult ALL (2009)
• Evolving Paradigms in the Therapy of Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia in Adults (2009)
• Management of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL) (2009)
• Acute Lymphoblastic Leukemia: An Historical Perspective (2008)
• Molecular Determinants of Treatment Response in Acute Lymphoblastic Leukemia (2008)
• The Treatment of Adults with Acute Lymphoblastic Leukemia (2008)
• Treatment of Acute Lymphoblastic Leukemia in Children and Adolescents: Peaks and Pitfalls (2008)
• Which Patients with Adult Acute Lymphoblastic Leukemia Should Undergo a Hematopoietic Stem Cell Transplantation? Case-Based Discussion (2007)
• Tumor-Specific Genetic Lesions and Their Influence on Therapy in Pediatric Acute Lymphoblastic Leukemia (2006)
• Myths and Lessons from the Adult/Pediatric Interface in Acute Lymphoblastic Leukemia (2006)
• Central Nervous System Disease in Acute Lymphoblastic Leukemia: Prophylaxis and Treatment (2006)
  
• Acute Lymphoblastic Leukemia: Older Patients and Newer Drugs (2005)

Acute Myeloid Leukemia (AML)

• Independent Prognostic Factors for AML Outcome (2009)
• Optimal Induction and Post-Remission Therapy for AML in First Remission (2009)
• What Is the Role of Reduced-Intensity Transplantation in the Treatment of Older Patients With AML? (2009)
• ASH Evidence-Based Guidelines: Is There a Role for Second Allogeneic Transplant After Relapse? (2009)
• Acute Myeloid Leukemia: The Challenge of Capturing Disease Variety (2008)
• Acute Myeloid Leukemia; Decided Victories, Disappointments, and Detente: An Historical Perspective (2008)
• Curative Strategies in Acute Promyelocytic Leukemia (2008)
• Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia (2008)
• Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia When a Matched Related Donor Is Not Available (2008)
• Genetic Pathways in the Pathogenesis of Therapy-Related Myelodysplasia and Acute Myeloid Leukemia (2007)
• Etiology and Management of Therapy-Related Myeloid Leukemia (2007)
• Prognostic Factors in Elderly Patients with AML and the Implications for Treatment (2007)
• Chromosome Aberrations, Gene Mutations and Expression Changes, and Prognosis in Adult Acute Myeloid Leukemia (2006)
• Controversies in Treatment of AML: Case-based Discussion (2006)
• New Strategies for the Treatment of Acute Myeloid Leukemia Including Antibodies and Other Novel Agents (2005)
• Childhood and Adolescent Lymphoid and Myeloid Leukemia (2004)

Acute Promyelocytic (Progranulocytic) Leukemia (APL)

• Treatment of Acute Promyelocytic Leukemia (2006)
• The Biology of Acute Promyelocytic Leukemia and Its Impact on Diagnosis and Treatment (2006)
• Management of APL in Developing Countries: Epidemiology, Challenges and Opportunities for International Collaboration (2006)

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